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Table 4 Comparison of exon creation/loss between human nonsense-mediated mRNA decay-specific and non nonsense-mediated mRNA decay-single exons

From: Noisy splicing, more than expression regulation, explains why some exons are subject to nonsense-mediated mRNA decay

Evolutionary patterns

Human (source)

Mouse (target)

Dog (outgroup)

NMD-specific

NonNMD-single

Conserved in target

+

+

+

23

436

Conserved in target

+

+

-

1

13

Lost in target

+

-

+

2

38

Created in source

+

-

-

9

66

Total

   

35

553

  1. Notes. NMD = nonsense-mediated mRNA decay. +, The orthologous exon exists in this lineage; -, The orthologous exon is not observed in this lineage.
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BMC Biology

ISSN: 1741-7007

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