Table 6 Differences in phospholipids associated with connexin hemichannels.
From: Connexin channels and phospholipids: association and modulation
Hemichannel | Headgroup | Linkage | Carbon atoms (number) | Saturation |
|---|---|---|---|---|
Cx26 | PE, PA, PI, PS. No unique species of PC. Predominantly anionic. | Fewer ether-linkages than unique to Cx32. | Range 28 to 42. Mean 34. Median 34. | Bimodal distribution. |
Cx32 | PC, PE, PA, PI. No unique species of PS. Mostly anionic, less than for Cx26. | More ether-linkages than in common or unique to Cx26. | Range 26 to 44. Mean 36. Median 38. | Broad distribution. Shorter chains more saturated. |
Cx26 and Cx32 | PC, PE, PA, PI, PS. Zwitterionic species approx. 50%, more than are unique to Cx26 or Cx32. | Similar ether-linkages to those unique to Cx26. | Range 28 to 38 + 44. Mean 35. Median 36. | Broad distribution. |