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Figure 9 | BMC Biology

Figure 9

From: Shaping mechanisms of metal specificity in a family of metazoan metallothioneins: evolutionary differentiation of mollusc metallothioneins

Figure 9

Nucleotide-based neighbour-joining tree of mollusc metallothioneins (MTs) comprising mussels and gastropods, with Eisenia foetida MT used as out-group. Pulmonate MTs appear grouped in separate clusters of metal-specific subfamilies (CuMTs, Cd/CuMTs and CuMTs). Accession numbers of GenBank entries used were as follows: Helix pomatia CdMT (HpCdMT), AAK84863 and AF399740; H. pomatia CuMT (HpCuMT), AAK84864 and AF399741. Biomphalaria glabrata CdMT, ACS91928 and GQ205374; B. glabrata CuMT, ACS91927 and GQ205373; B. glabrata Cd/CuMT, ACS91929 and GQ205375; Cantareus aspersus CdMT, ABL73910 and EF152281; C. aspersus CuMT, ABM55268 and EF178297; C. aspersus Cd/CuMT, ABM92276 and EF206312; Nesiohelix samarangae CdMT, ACC17831 and EU437399; Megathura crenulata MT, AY102647; Littorina littorea MT, AY034179; Mytilus edulis MT-10, AJ007506 and EF140765; Crassostrea virginica MT-1A, AY331697; C. virginica MT-1B, AY331699; Meretrix lusoria MT, AY525635; Perna viridis MT-2, F092972; Dreissena polymorpha MT, DPU67347; Unio tumidus MT, EF185127; Corbicula fluminea MT, EF185126; Eisenia foetida MT, AK236886.

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