Table 1 Axon initial segment (AIS) origin, length, distance from the soma and voltage-gated sodium (Nav) channel composition in α and γ motor neurons (MNs)
AIS origin | Length (μm) | Distance from the soma (μm) | Nav composition | ||
|---|---|---|---|---|---|
Nav1.1/Nav1.6 | Nav1.6 | ||||
α-MN | Dendritic (15%) (n = 19) | 29.5 ± 3.2 (n = 6) | 16.9 ± 13.2 (n = 6) | 100% (n = 18) | 0% (n = 18) |
Somatic (85%) (n = 61) | 29.3 ± 5.4 (n = 26) | 5.6 ± 3.8 (n = 26) | 79.8%, (n = 35) | 20.2% (n = 35) | |
γ-MN | Somatic (100%) (n = 69) | 28 ± 8.7 (n = 69) | 8.1 ± 3.5 (n = 69) | 81.2% (n = 43) | 18.8% (n = 43) |