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Table 1 Axon initial segment (AIS) origin, length, distance from the soma and voltage-gated sodium (Nav) channel composition in α and γ motor neurons (MNs)

From: Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B

  AIS origin Length (μm) Distance from the soma (μm) Nav composition  
     Nav1.1/Nav1.6 Nav1.6
α-MN Dendritic (15%)
(n = 19)
29.5 ± 3.2
(n = 6)
16.9 ± 13.2
(n = 6)
100%
(n = 18)
0%
(n = 18)
  Somatic (85%)
(n = 61)
29.3 ± 5.4
(n = 26)
5.6 ± 3.8
(n = 26)
79.8%,
(n = 35)
20.2%
(n = 35)
γ-MN Somatic (100%)
(n = 69)
28 ± 8.7
(n = 69)
8.1 ± 3.5
(n = 69)
81.2%
(n = 43)
18.8%
(n = 43)