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Figure 4 | BMC Biology

Figure 4

From: Enrichment of statistical power for genome-wide association studies

Figure 4

Statistical power of four statistical methods. The four methods are general linear model (GLM), mixed linear model (MLM), compressed MLM (CMLM), and enriched compressed MLM (ECMLM). The CMLM was performed with the un-weighted pair group method with arithmetic mean clustering algorithm and the average algorithm for calculating group kinship. The ECMLM was performed by the best combination of three group kinship algorithms and eight clustering algorithms. The statistical power was evaluated on a simulated phenotype with the quantitative trait nucleotide (QTN) effect added to observed phenotypes. The size of the QTN effect is expressed in the unit of phenotypic standard deviation. The corresponding proportions of total phenotypic variance explained are displayed in the parentheses. The observed phenotypes are (A) body mass index in human, (B) Orthopedic Foundation for Animals score in dog, and flowering time in both (C) maize and (D) Arabidopsis.

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