Figure 5

Whole body, liver wet weight and relative liver weight analysis of one-week-old mice. A) Significantly increased body weights were noted in Grb10 ^m/+ compared to wild type and Dlk1 ^+/p and in Grb10 ^m/+/Dlk1 ^+/p compared to Dlk1 ^+/p mice whereas weights of Dlk1 ^+/p animals did not differ from wild types. B) Analysis of wet weights of the livers revealed significant enlargement in Grb10 ^m/+ compared to wild type and Dlk1 ^+/p mice and in Grb10 ^m/+/Dlk1 ^+/p compared to Dlk1 ^+/p animals. C) No differences were found in relative liver weights. D) Table summarising results of statistical analysis. All values represent means ± SEM, analysed using one way ANOVA with Tukey’s post-hoc analysis. WT n = 10, Dlk1 ^+/p n = 9, Grb10 ^m/+ n = 15, Grb10 ^m/+/Dlk1 ^+/p n = 8; * P <0.05; *** P <0.001. ANOVA, analysis of variance; SEM, standard error of the mean; WT, wild type.