Figure 6From: Antagonistic roles in fetal development and adult physiology for the oppositely imprinted Grb10 and Dlk1genesHistology of neonatal and adult livers stained with Oil Red O. A) An increased number of lipid droplets was observed in cryosectioned Grb10 m/+ and Grb10 m/+/Dlk1 +/p neonatal livers following Oil Red O staining. B) An increased number of lipid droplets was observed in Oil Red O stained adult livers from Dlk1 +/p knockout mice. Images presented in Panels A and B show representative sections for each of the analysed genotypes. C) Quantification of histological sections (from three individuals for each genotype) of neonatal liver stained with Oil red O (percentage of area stained), showing increased staining for both Grb10 m/+ and Grb10 m/+/Dlk1 +/p livers. D) Table summarising results of statistical analysis of data in C. All values represent means ± SEM and have been subject to one way ANOVA with post hoc Tukey’s analysis. WT n = 3, Dlk1 +/p n = 3, Grb10 m/+ n = 3 and Grb10 m/+/Dlk1 +/p n = 3; ** P <0.01, ***P <0.001. ANOVA, analysis of variance; SEM, standard error of the mean; WT, wild type.Back to article page