Fig. 2

Comparison of model predictions with experimental data for Canton-S populations. (a) Comparison of final DDT-R frequencies from experimental populations (Low, Mid, High) and nHW, with initial and model prediction frequencies. Empirical data (open bars) is presented as mean frequency with standard error bars. Low, Mid, High population data are for generation 5 while nHW population data are for generation 10. (b) Comparison of nHW Canon-S population cage allele trajectories with model predictions. Black lines represent DDT-R allele frequencies over 10 generations. All six population cages started at x _R = 0.5 (generation 0) with either 50 RR males and 50 SS females or the reciprocal cross. Hence, all genotypes were RS in generation 1. Red dashed line and square symbols represent the allele frequencies predicted. Population cage frequencies are significantly different from model predictions at generations 2 to 5 (asterisks, t-tests of logit transformed frequency, p <0.05) but match model predictions thereafter (all p >0.05)