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Fig. 2 | BMC Biology

Fig. 2

From: Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development

Fig. 2

Mesenchymal-specific deletion of Apc resulted in lung malformation. a Apc CKO induced from E10.5 led to thoracic hemorrhage indicated by dashed line at E14.5. b Gross view of isolated lungs showed that the Apc CKO caused mesenchymal hyperplasia at E12.5, growth arrest at E13.5, and massive hemorrhage at E14.5. No significant change was observed between WT and Apc heterozygous conditional knockout (HT) lungs

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BMC Biology

ISSN: 1741-7007

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