The relative importance of kinetic mechanisms and variable enzyme abundances for the regulation of hepatic glucose metabolism – insights from mathematical modeling

Table 2 Average curve difference Δ

Scenario	Difference of diurnal HGP/HGU profile
Scenario	Fasted	Fed
No change of enzyme abundance	0.25	1.54
No allosteric effectors	0.60	0.47
No interconversion	0.89	0.88

ISSN: 1741-7007