Fig. 3From: Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformationComparison of crystal structure of N-Cbl (PDB 2Y1M) and the model derived from iterative normal mode analysis. The unphosphorylated, catalytically competent N-Cbl from the crystal structure (PDB 2Y1M) is coloured cyan and is superposed with the normal mode analysis-refined model. The TKBD is shown in blue, the RING domain in orange and the LHR in yellow as a surface modelBack to article page