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Fig. 3 | BMC Biology

Fig. 3

From: Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation

Fig. 3

Comparison of crystal structure of N-Cbl (PDB 2Y1M) and the model derived from iterative normal mode analysis. The unphosphorylated, catalytically competent N-Cbl from the crystal structure (PDB 2Y1M) is coloured cyan and is superposed with the normal mode analysis-refined model. The TKBD is shown in blue, the RING domain in orange and the LHR in yellow as a surface model

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