Fig. 3

Time-lapse analysis in r6 neural crest stream shows frequent collisions with endothelial cells. a Schematic of embryo during time-lapse imaging illustrating the neural crest migrating away from the neural tube and endothelial cells moving in the reverse direction. b Example of an endothelial cell (yellow) that collides with the dense r6 neural crest stream, changes direction, and moves to a less populated area. Two neural crest cells (cyan) that interact with the endothelial cell migrate distally. c Endothelial nuclei (yellow) changing from a round to elongated shape as the cell squeezes through neural crest. Scale bars 50 μm