Human chromosome number
|
Number of dosage-balanced ohnologsa
|
Trisomy syndrome
|
Frequency (number of live births)b
|
---|
21
|
61
|
Down's
|
1/700
|
18
|
98
|
Edward's
|
1/5000
|
13
|
138
|
Patau
|
1/16,000
|
-
aIdentified from gene trees in Ensembl v86 [109] as genes that duplicated at the base of the vertebrate tree with no subsequent SSD
-
bFrequency data from [90] and ghr.nlm.nih.gov/trisomy-18; ghr.nlm.nih.gov/trisomy-13