Fig. 1
From: Precise A•T to G•C base editing in the zebrafish genome
Comparison of the original ABE system and optimized zABE7.10 system in zebrafish. a Schematic diagrams of two adenine base-editing system, pCMV-ABE and zABE7.10. The zABE7.10 system is a zebrafish codon optimized version by IGE. b Selected sites that can work efficiently in zebrafish using BE system or Target-AID system. Target sequence (black) and PAM region (blue) are indicated. c Sequencing result at the ddx17-g1 target in pCMV-ABE system in zebrafish. d Sequencing result at the ddx17-g1 target in zABE7.10 system in zebrafish