Fig. 1

LncRNAs sequence features in C. elegans. a Nucleotide compositions of exons and introns of lncRNAs and protein-coding genes classified according to their gene model. b GC content variation across metagenes. The x-axis represents non-overlapping windows each including 10% of the sequences across multi-exonic protein-coding and lncRNA loci; the solid lines represent respectively the 95% confidence interval, median and 5% confidence interval. The black band represents the GC content of flanking intergenic sequences. c Nucleotide conservation (PhyloP score) comparison among intergenic sequences, multi- or mono-exonic lncRNAs and protein-coding loci. d Enrichment of lncRNAs for chromatin annotations identified by Daugherty et al. [28]. Transcribed gene body: ensemble of ChromHMM states characterised by H3K79me2, H3K36me3, H3K4me1 and H4K20me1. Repressed enhancers: ensemble of ChromHMM states characterised by H3K4me1 and H3K27me3. Low signal: regions without histone modification signals