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Fig. 2 | BMC Biology

Fig. 2

From: Comparative whole genome DNA methylation profiling across cattle tissues reveals global and tissue-specific methylation patterns

Fig. 2

DNA methylation landscapes of PMDs in various cattle tissues. a Distribution analysis of the PMD using chr7 as an example with different genome tracks, including from the top to bottom: CG methylation level; CG density; gene number; placenta gene expression (in log2 scale); HMR numbers in the placenta, sperm, blood, lung, and liver; H3K27Ac (liver) and H3K4me3 (liver). Three DNA methylation-level drops are labeled out with rectangles. b Comparison of the location between PMDs and TADs. c Cluster analysis of cattle samples by the PMD. The PMDs were merged into PMD regions for all the samples. We calculated the ratio of the PMD of each sample to the merged PMD regions, which was then used for the cluster analysis

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