Fig. 1

Temporally discrete P. yoelii parasitemia profiles in Taconic C57BL/6N mice. C57BL/6N mice from Taconic Biosciences were infected with P. yoelii 17XNL followed by the analysis of parasite burden. a Percent parasitemia was measured in Taconic mice obtained from a single C57BL/6N production suite, Isolated Barrier Unit™ (IBU15), on the indicated date. Data are from 3 to 5 mice per group.. b Area under the parasitemia curve (AUC) from a with each symbol representing an individual mouse. c Percent parasitemia in Taconic mice obtained from specific C57BL/6N IBUs. Data are cumulative results with 8–10 mice per group from two experiments. d AUC from c with each symbol representing an individual mouse. Data are mean ± S.E. b,d. One-way ANOVA with Tukey’s multiple comparisons test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001