Table 4 Mean ΔΔG (in kcal/mol) for μSBSs from \(\mathcal {M}_{\text {PoP}}\) obtained from SBSs at different codon positions (I, II, III). In the lower part of the table, the mean ΔΔG is computed by considering also the synonymous mutations (with ΔΔG=0) and the degeneracy (the number of SBSs leading to a μSBS)
Position | 〈ΔΔG〉 | Stab (%) | Neut (%) | Dest (%) |
|---|---|---|---|---|
Without synonymous mutations and degeneracy | ||||
I | 0.65 | 3 | 49 | 48 |
II | 0.91 | 5 | 36 | 59 |
III | 0.51 | 4 | 50 | 46 |
With synonymous mutations and degeneracy | ||||
I | 0.64 | 3 | 50 | 47 |
II | 0.91 | 5 | 36 | 59 |
III | 0.16 | 2 | 84 | 14 |