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Fig. 3 | BMC Biology

Fig. 3

From: Population structure and pharmacogenomic risk stratification in the United States

Fig. 3

Self-identified race/ethnicity (SIRE) versus genetic ancestry (GA) for partitioning pharmacogenomic (PGx) variation. ac Regression of pairwise PGx variant effect allele frequency differences calculated using SIRE (y-axis) versus the corresponding GA groups (x-axis). Results of two statistical tests are shown for each of three pairwise group regressions. Test 1 evaluates whether SIRE and GA PGx allele frequencies are correlated, and test 2 evaluates that amount of additional resolution on PGx variant divergence that is provided by GA compared to SIRE. Details on each test are provided in the text

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