Fig. 6

A phylogenetic tree of trypanothione (TR; green background), thioredoxin (TrxR; blue), and glutathione reductases (GR; yellow) based on a trimmed alignment of 352 amino acids. Nodes exhibiting maximal bootstrap support and posterior probability (PP) are marked by black circles; gray circles signify ≥ 90% bootstrap support and PP ≥ 0.9. Only bootstrap support and PP values ≥ 0.6 are shown. Species abbreviations in protein IDs are as follows: Ahoya, Azumiobodo hoyamushi; Baya, Blechomonas ayalai; BS, Bodo saltans; Cfas, Crithidia fasciculata; Ecoli, Escherichia coli; Egra, Euglena gracilis; Ehux, Emiliania huxleyi; EMOLV, Endotrypanum monterogeii; Egym, Eutreptiella gymnastica; Hpha, Hemistasia phaeocysticola; Hsap, Homo sapiens; Linf, Leishmania infantum; LmjF, Leishmania major; Lmex, Leishmania mexicana; Lpyr, Leptomonas pyrrhocoris; Ndes, Neobodo designis; PCON, Paratrypanosoma confusum; Perk, Perkinsela sp.; PhF_6, prokinetoplastid species PhF-6; PhM_4, prokinetoplastid species PhM-4; Rhum, Rhynchopus humris; Rcos, Rhabdomonas costata; Sspe, Sulcionema specki; Tbor, Trypanoplasma borreli; Tbru, Trypanosoma brucei; Tcru, Trypanosoma cruzi; Tgra, Trypanosoma grayi