Fig. 2

Characterization of core promoters in locusts. a Patterns of the GC content in the 2-kb flanking region of transcription start sites. The deviation of the GC content in sliding windows was determined using the GC content normalized to the mean GC content. b CpG occurrence in the 2-kb flanking region of transcription start sites. Normalized CpG contents (CpG observed/expected, CpG oe) and GC contents were computed in a 50-bp sliding window across 4-kb regions centered on the dominant TSSs. c De novo motif discovery in the 20 to 40 bp region upstream of the dominant OTSSs of core promoters. d TATA-box signals in the upstream regions of PyPu dinucleotides in the core promoters with different promoter shapes. e Density distribution of the PSS values of promoters with ubiquitous and restricted TSC expression. f Shannon index of OTSS diversity in genic core promoters. g Shannon index of OTSS diversity in genic core promoters in the down-sampled data. h Shannon diversity index of OTSSs in the core promoters with different promoter shapes. i Density of SNPs flanking the transcription start sites. The TSCs flanked by repetitive elements were not included in this comparison. The red asterisk indicates P < 2.2e−16 according to the Wilcoxon rank-sum test