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Fig. 3 | BMC Biology

Fig. 3

From: Natural abundance isotope ratios to differentiate sources of carbon used during tumor growth in vivo

Fig. 3

CATSIR applied to measure the sources of carbon used for tumor growth in D. melanogaster larvae. a Cephalic complex total carbon mass measurements of the same larvae as in Fig. 2b. b The calculated amounts of carbon from the food or host tissues being incorporated into the tumor between day 6 and 8, calculated from the SIRMS data shown in Figs. 2b and 3a. c Percentage of carbon added between day 6 and day 8 derived from host sources. All measurements in Fig. 3 are from four independent biological replicates with the exception of three replicates for the C4 day 6 set where one replicate was lost because there was not enough carbon in it to obtain a reliable measurement. All indicated statistical test p values are from an unpaired two-sided t-test between the indicated groups. Box-plots are used for visualizing the data with default settings for geom_boxplot in R; the median as a line inside boxes extending from the 25th percentile to the 75th percentile and whiskers extending maximally to 1.5x of the inter-quartile range

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