Genes underlying the evolution of tetrapod testes size

Table 1 Target genes for testis size

Gene	D	df	N_gene	N_codons	N_Taxa	Outgroup
Alkbh5	1275.71*	375	193	373	101	Xenopus
Cdkn2c	582.93*	440	226	166	111	Latimeria
Dmrtb1	793.65*	388	200	151	97	Latimeria
Dnah11	5209.60*	311	159	4465	74	Latimeria
Lrp8	1790.75*	422	217	986	111	Latimeria
Ndc1	1266.98*	472	243	787	115	Latimeria
Nlrp3^a	517.70*	232	120	1024	63	Loxodonta
Pld6	1057.41*	400	205	229	104	Latimeria
Sp4	1555.50*	464	239	757	117	Latimeria
Spata6	1179.64*	452	233	488	112	Latimeria
Sp8	1660.07*	319	163	506	87	Latimeria
Ubb	534.74*	300	156	126	79	Xenopus

Sample sizes, outgroups, and likelihood ratio (D) test results comparing a global vs. local model of molecular evolution are shown for each gene. N_gene is the number of taxa included in the model used to calculate dN and dS across the total number of codons (N_codons). N_taxa is the final number of taxa used in our regression models (Figure 3). *All comparisons are significant at the p < 0.001 level . ^aNote that Nlrp3 is restricted to mammals only—all other genes are analysed across tetrapods

ISSN: 1741-7007