Fig. 3From: Long-term dynamics of the human oral microbiome during clinical disease progressionNetwork cartography and profiles of network centralities. a–c Species are assigned roles in the network. The metrics to assess the roles in the sub-community include within-module degree, which measures how well a particular species is connected to others in the same sub-community (module), and among-module connectivity, which measures how a species is linked to other modules in the network. Species are classified as hub connectors, hub kinless, non-hub connector, non-hub kinless, peripheral, provincial, and ultra-peripheral [23]. d Temporal evolution of degree centrality in the co-occurrence networks of the different groups. e Temporal evolution of betweenness centrality in the co-occurrence networks of the different groups. f Temporal evolution of the formation of edges in the networks of the different groups. The grey zones in d–f represent the period after treatmentBack to article page