Fig. 10
From: A unified evolutionary origin for the ubiquitous protein transporters SecY and YidC
Model for the evolution of YidC and SecY. Charged side chains and termini are indicated only at stage 1, by grey symbols. Asterisks indicate the pore ring or groove end residue in H5. At top, additional components of the secretory pathway label a range of stages at which they may have arisen. Models show archaeal YidC and its partner EMC6-like protein (M. jannaschii MJ0480 and MJ0606), bacterial YidC (B. halodurans YidC2, 3wo6), and SecY (G. thermodenitrificans SecY, 6itc)