Fig. 4

Phenotypes of LEA-1 are specific to conditions of stress. A Lifespan of lea-1Δ mutants is not significantly different from WT (N2) animals (p = 0.40, log-rank test). lea-1(tm6452) mutants were slightly short-lived relative to WT (N2) animals (p = 0.005, log-rank test). B Lifespan is not significantly altered by lea-1Δ or lea-1(tm6452) mutations in a daf-2 mutant background (p = 0.11, p = 0.07, respectively, log-rank test). C There are no significant differences in brood size of lea-1Δ (p = 0.97, n = 3, unpaired T test) or lea-1(tm6452) mutants (p = 0.41, n = 3, unpaired T test) relative to N2 worms. Brood size of individual worms from independent replicates is shown. The mean is also shown and error bars represent 95% confidence intervals