Table 4 Water consumption in treated and untreated wt and Mecp2y/− male mice. D-JNKI1 did not change the water intake in both wt and Mecp2 y/−-treated mice
From: JNK signaling provides a novel therapeutic target for Rett syndrome
Water intake | Wt (g) | Wt + D-JNKI1 (g) | Mecp2y/− (g) | Mecp2y/− + D-JNKI1(g) | Significance | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Weeks | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Wt vs wt+D-JNKI1 | Mecp2y/− vs Mecp2y/− +D-JNKI1 |
3 | 4.6283 | 0.4713 | 5.5329 | 0.9571 | 2.7983 | 0.4139 | 4.5100 | 1,4200 | n.s. | n.s. |
4 | 5.3220 | 0.5939 | 5.6950 | 0.6502 | 3.0389 | 0.2847 | 2.8580 | 0,2901 | n.s. | n.s. |
5 | 5.9850 | 0.5199 | 5.3333 | 0.3999 | 3.0300 | 0.3300 | 2.6360 | 0,2393 | n.s. | n.s. |
6 | 5.1850 | 0.6216 | 4.5763 | 0.3882 | 2.6943 | 0.2691 | 3.2700 | 0,4998 | n.s. | n.s. |
7 | 3.8911 | 0.4108 | 4.3420 | 0.5317 | 3.2786 | 0.3967 | 2.8500 | 0,6756 | n.s. | n.s. |