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Table 1 Overall effects (lnRR), 95% confidence intervals (CI) and heterogeneity statistics as estimated by multi-level meta-analysis. HOMA Homeostatic Model Assessment (a measure of insulin sensitivity)

From: Meta-analysis links dietary branched-chain amino acids to metabolic health in rodents

Trait lnRR CI σ2Experiment σ2Residual I2Total I2Experiment
Plasma BCAAs 0.275 0.061 to 0.489 0.035 0.103 99.87 25.54
Plasma isoleucine 0.122 0.003 to 0.241 0.077 0.137 99.91 35.78
Plasma leucine 0.319 0.221 to 0.416 0.046 0.094 99.14 32.69
Plasma valine 0.198 0.086 to 0.310 0.054 0.136 99.81 28.41
Glucose AUC 0.193 0.072 to 0.314 0.010 0.093 84.21 8.53
Plasma glucose 0.004 − 0.036 to 0.043 0.007 0.006 79.26 41.51
Plasma insulin 0.038 − 0.056 to 0.131 0.004 0.183 83.02 1.71
HOMA 0.019 − 0.108 to 0.146 0.000 0.243 74.81 0.00
Mass 0.010 − 0.024 to 0.043 0.022 0.024 98.43 47.49
Percent fat mass 0.017 − 0.106 to 0.140 0.014 0.063 89.63 16.07
Food intake − 0.067 − 0.106 to − 0.028 0.018 0.027 94.45 37.67
Energy intake − 0.058 − 0.093 to − 0.023 0.013 0.044 99.98 22.37