Meta-analysis links dietary branched-chain amino acids to metabolic health in rodents

Table 1 Overall effects (lnRR), 95% confidence intervals (CI) and heterogeneity statistics as estimated by multi-level meta-analysis. HOMA Homeostatic Model Assessment (a measure of insulin sensitivity)

Trait	lnRR	CI	σ²_Experiment	σ²_Residual	I²_Total	I²_Experiment
Plasma BCAAs	0.275	0.061 to 0.489	0.035	0.103	99.87	25.54
Plasma isoleucine	0.122	0.003 to 0.241	0.077	0.137	99.91	35.78
Plasma leucine	0.319	0.221 to 0.416	0.046	0.094	99.14	32.69
Plasma valine	0.198	0.086 to 0.310	0.054	0.136	99.81	28.41
Glucose AUC	0.193	0.072 to 0.314	0.010	0.093	84.21	8.53
Plasma glucose	0.004	− 0.036 to 0.043	0.007	0.006	79.26	41.51
Plasma insulin	0.038	− 0.056 to 0.131	0.004	0.183	83.02	1.71
HOMA	0.019	− 0.108 to 0.146	0.000	0.243	74.81	0.00
Mass	0.010	− 0.024 to 0.043	0.022	0.024	98.43	47.49
Percent fat mass	0.017	− 0.106 to 0.140	0.014	0.063	89.63	16.07
Food intake	− 0.067	− 0.106 to − 0.028	0.018	0.027	94.45	37.67
Energy intake	− 0.058	− 0.093 to − 0.023	0.013	0.044	99.98	22.37

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