Fig. 5

Comparison of healthy donors’ and WAS patients’ NCs behavior. A–C Typical for healthy donors FOV with growing thrombi and crawling granulocytes. D–F Typical for healthy donors FOV with growing thrombi and crawling granulocytes. G–I Quantitative comparison of the granulocyte behavior of healthy donors (white) and WAS patients (green): the ratio of granulocyte number to thrombus area (G), average velocities of the crawling granulocytes (H), amounts of spread granulocytes and lymphocytes (slow NCs) (I) for n = 10 healthy donors and n = 7 WAS patients (raw data could be found at https://doi.org/10.6084/m9.figshare.18359408.v1, individual data values are given in the Additional Table 3). Statistical significance was calculated with Mann-Whitney test, ** corresponds to p < 0.01, *** corresponds to p < 0.001