Fig. 5
From: Fluid shear stress enhances T cell activation through Piezo1
FSS enhances activation of primary human T cells. A Representative flow plot of ZAP70 phosphorylation of CD4-positive T cells. Graphs of ZAP70 phosphorylation for CD4- and CD8-positive T cells treated with FSS and antibodies (N=3). B Representative flow plot of NF-κB phosphorylation of CD4-positive T cells. Graphs of NF-κB phosphorylation for CD4- and CD8-positive T cells treated with FSS and antibodies (N=3). C Representative flow plot of IL-2 expression in CD4-positive T cells. Graphs of TNF-α, IL-2, and IFN-γ for CD4- and CD8-positive T cells treated with FSS and antibodies (N=3). Paired t tests were used to measure statistical significance between treatment groups. * p<0.05, ** p<0.01 *** p<0.005. Error bars are SD