Fig. 4

Non-overlapping distribution of highly active and highly connected neuronal populations in the whole larval zebrafish brain. A Schematic diagram showing the analysis pipeline applied to the whole brain spontaneous activity data from larval zebrafish (n=10). B Connectivity levels (Y-axis) of all neurons sorted based on their activity (X-axis) in an example subject. Red and blue boxes denote neurons of high activity and high functional connectivity, respectively. The dotted circle denotes where highly active and highly connected neurons are expected. C The population distribution curve of all neurons with different levels of activity and functional connectivity. Note that neurons that have high activity and high connectivity are non-existent. The number of replicates used is 10