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Fig. 1 | BMC Biology

Fig. 1

From: Experimental demonstration of tethered gene drive systems for confined population modification or suppression

Fig. 1

Standard and tethered homing drive comparison. Populations are shown at three different times after drive release. a A standard homing drive has no threshold frequency, and it can spread to a wild-type population after a small release. b A tethered homing drive cannot increase in frequency within a wild-type population since it lacks Cas9 for drive conversion. c A TARE drive can spread after a moderate release, followed by a tethered homing drive after a small release. d A sufficiently small introduction of TARE drive to a population will not allow the TARE drive to spread, which will in turn prevent spread of the tethered homing drive

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