Fig. 6
Prenatal exposure to E3 alters gene methylation in the adult offspring brain. A Heat maps showing the top 3000 differential CpG sites with altered methylation in E3-treated compared to control frontal cortex. B Grouping top 3000 genes according to physiological system development and function using the Ingenuity (IPA) software. C Heat maps of top 3000 CpG sites with altered methylation in hippocampus. Grouping of top 2000 of D hypermethylated and E hypomethylated differential CpG sites according to physiological system development and function using Ingenuity