Fig. 5
From: Optimization of the antimicrobial peptide Bac7 by deep mutational scanning
Efficacy of Bac7PS in a murine model. a Efficacy study scheme. Drugs are applied to mice infected with E. coli ATCC 25922. Bacteria and drugs are administered intraperitoneally (IP). b Survival rates after infection. Mice are infected with E. coli ATCC 25922 and then treated with CIP as positive control and without a drug (vehicle) as the negative control. The study was performed for each condition as described in a