Fig. 1
From: Polycomb contraction differentially regulates terminal human hematopoietic differentiation programs
H3K27me3 signatures are shared across functionally distinct human CD34+ hematopoietic progenitor populations. A Schematic of the experimental design and color legend (shown in the bottom right corner) for the 8 cell types analyzed. Unsupervised hierarchical clustering and heatmap of pairwise Spearman correlations for protein coding gene RPKM values (B), H3K4me3 coding gene promoter (± 2 Kb) density (C), and H3K27me3 coding gene promoter density (D) across cell types indicated by color. Genome browser view of H3K27me3 (left panel) and H3K4me3 (right panel) density tracks across cell populations indicated by track color at the CEBPA (E) and GATA1 (F) locus. Unsupervised hierarchical clustering and heatmap showing pairwise Spearman correlation of H3K4me3 (G) and H3K27me3 (H) densities genome-wide