Fig. 4.
Selective regions associated with high-altitude adaptation in P. mira. a–c Domestication signals in accessions originating in high-altitude region compared to those in low-altitude. The signals were defined by the top 5% of πratio (a), Tajima’s D (b), and FST values (c). d Distribution of expression of genes induced by low temperature and UV of P. mira. Grey dots indicate the background genes and red dots indicate selective genes associated with high-altitude adaptation. e Detailed π ratio and FST values in the genome region of the candidate gene, Pmi02g3025 (pointed by the dashed line), which was substantially induced by low temperature. f Detailed Tajima’s D in the genome region of the candidate gene Pmi02g3025. g A. thaliana plants expressing Pmi02g3025 gene (OE) and the control (WT) treated with low temperature. h Genotypes (K indicates G/T) of a variation (Chr. 2: 28,612,439 bp) located at the promoter of Pmi02g3025 in accessions from different altitude regions