Fig. 6

Heatmap profiling of GFs for frequently observed sequence types. Heatmap profiles have been derived by unsupervised clustering of 674 E. coli genomes with common sequence types (STs), i.e., at least 10 genomes in each ST. There are 6244 GFs included in the analysis with presence in at least 10 genomes and at most 640 genomes, respectively. The yellow color represents present and black color represents absent GFs (column) in the genome (row), respectively. The ST (1) and phylogroups (2) are labelled accordingly. The dendrograms for genomes and GFs are shown in rows and columns, respectively. The six most distinguishing patterns are highlighted in red boxes representing Cluster 1 (Rare in ST11), Cluster 2 (Common in B2), Cluster 3 (Common in ST131), Cluster 4 (Rare in ST131), Cluster 5 (B1-shiga), and Cluster 6 (Common in ST11). The blue box represents the cluster with T6SS-2 in ST11