Fig. 5

Stage of growth inhibition of P. falciparum during 48 h of 200 nM YAT2150 treatment. The drug was added to synchronized parasite cultures at the ring or trophozoite stages. Giemsa-stained blood smears were prepared at the indicated time points between 0 and 48 h of incubation, and the numbers of ring stages, early trophozoites, late trophozoites, and schizonts were counted in samples of at least 100 pRBCs for each time point. A Bars indicate the percentages of developmental stages present in the respective blood smears. B Representative images of pRBCs in the assay where YAT2150 was added at ring stage