Fig. 6

Cellular and subcellular targeting of YAT2150. A Absorbance and emission spectra of YAT2150 in the presence of Aβ40. B Flow cytometry analysis of a YAT2150-stained desynchronized P. falciparum culture where 30,000 events were recorded. The fraction of YAT2150-positive RBCs and pRBCs is indicated (%), the latter consisting of late rings, trophozoites and schizonts, the three stages represented in the cartoons. C Confocal fluorescence microscopy examination of P. falciparum blood stages. The arrowhead indicates an individual merozoite. DIC: differential interference contrast image