Fig. 1From: Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chainsSequences of the A λ and B κ variable domain of the germline sequences. The mutations in the sequences of the IgLC samples compared to the corresponding germline sequence are labelled. The relative proportion of mutations located in the CDRs are plotted (C). Three-dimensional structural models of the variable regions of the λ (D) and κ (E) are visualised with PyMOL 2.4 (Schrödinger). The mutated amino acids in the investigated IgLCs are highlighted in colourBack to article page