Fig. 4
From: Detection and characterization of constitutive replication origins defined by DNA polymerase epsilon
Similarity between various replication origin detection methods. A Results obtained using the multiple vector alignment algorithm for chromosome 1, each row represents one origin and the color scale corresponds to the fraction of methods in which it was detected; the blue line represents the replication time data. B Enlarged fragment of panel A for 10–20-Mb region of chr1. C Heatmap showing the overall correlation between ORI detection methods, including a set of 5000 random genomic positions for comparison. The correlations are obtained using a dynamic programming-based vector alignment algorithm (see the “Methods” section)