Fig. 2
From: Efficient prioritization of CRISPR screen hits by accounting for targeting efficiency of guide RNA
Schematic design and data quality control of tiling array library CRISPR screening. A Schematic diagram of the library construction procedure and paired-end sequencing for simultaneous detection of guide RNA and the reporter sequence. B Tiling array library CRISPR screening workflow. C Correlation of indel frequencies between two replicates of day 21 samples. D Correlation of log fold changes between two replicates of day 21 samples. R indicates Pearson correlation coefficient r and p value is calculated by two-tailed test. E Indel frequencies at indicated timepoints from the tiling array library. The black line indicates the median indel frequency