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Fig. 1 | BMC Biology

Fig. 1

From: Hypoxia induces alterations in tRNA modifications involved in translational control

Fig. 1

RNA modification landscapes in mouse multiple tissues. A Relative percentage of modified and unmodified four nucleotides (adenine, uracil, cytosine, and guanine) in mouse total RNA, tRNA-enriched fragments, and 17–50-nt sncRNAs. The sum of all modified and unmodified nucleotides abundance was considered as 100 and the percentage was calculated by the average of each nuclear base across six tissues (n = 3, Additional file 10). B The relative proportion of detected RNA modifications across six tissues, the sum of all RNA modifications was considered as 100 and the percentage was calculated by the average of each modification across six tissues. C, E, G The heatmaps showed the relative expression levels of each RNA modification to average across six mouse tissues in total RNA, tRNA-enriched fragments, and 17–50-nt sncRNAs. D, F, H Principal component analysis (PCA) of RNA modifications in total RNA, tRNA-enriched fragments, and 17–50-nt sncRNAs across six mouse tissues

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