Fig. 6
From: Hypoxia induces alterations in tRNA modifications involved in translational control
Altered signature of RNA modifications in liver individual endo-tRNA by hypobaric hypoxia exposure. A The significant difference of RNA modifications in liver individual endo-tRNAAla, tRNAVal, tRNAGlu, tRNAGly, and tRNALeu between NC and Hypo groups. B The retar graph shows the altered pattern of RNA modifications in liver individual endo-tRNAAla, tRNAVal, tRNAGlu, tRNAGly, and tRNALeu between NC and Hypo groups (n = 3, Additional files 10 and 11). C Stability of liver individual endo-tRNAAla, tRNAVal, and tRNAGly against RNase A/T1 and fetal bovine serum (FBS). D Expression levels of individual endo-tRNAAla, tRNAVal, and tRNAGly in the liver, which showed the represent northern blot result of three times independent repeats. E The levels of Am and m2G in liver individual endo-tRNAAla, tRNAVal, tRNAGlu, tRNALeu, and tRNAGly (n = 3, Additional files 10 and 11). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; NB, northern blot. All results are shown as mean ± SEM. Statistical analysis was conducted using Student’s t-test unpaired