Fig. 4

The lineage and characteristics of myeloid cells in atherosclerotic lesions. a t-SNE plot of 13,963 myeloid cells. DC, dendritic cells. Mono, monocytes. Mac, macrophages. b Heatmap showing the normalised average expression of selected myeloid cells function-associated genes in each cell subpopulation. c Feature plots of canonical marker genes. d Line chart of tissue prevalence for each cell type estimated by Ro/e score. e Gene set enrichment analysis of monocyte subsets. f Dot plot showing average expression of foamy cell-related genes in macrophage subsets