Fig. 11
From: The retinal pigment epithelium displays electrical excitability and lateral signal spreading
Effects of nifedipine and 18α-GA on the delayed inward current. A–C Voltage clamp recordings in control conditions (A), after application of 10 μM nifedipine (B), and after wash-out (C). D I–V relations for the delayed inward currents from A to C (inward 2). E Bar plot summarizes changes in the peak delayed inward current in 5 cells in the presence of 10 μM nifedipine; paired t-test was used for the statistical comparison. F Cells were first exposed to 10 μM nifedipine and then, after wash-out of nifedipine, to 10 μM 18α-GA; bar plot shows changes in Cm (n = 6; P = 0.002, paired t-test). G–J Voltage clamp recordings in control conditions (G), after application of 10 μM 18α-GA (H), and, after wash-out, 10 μM TTX (I); J I–V relations for this experiment. In panels F–J, recordings were performed with Cs+ in the pipette solution