Fig. 6

Histone acetylation H3K27ac and H2A.Zac correlate with stage specific gene expression in ring stage parasites and female gametocytes. A Average profile plots of log₂-transformed ChIP/Input signals from H2A.Zac (n = 2 for female gametocytes, n = 1 for male gametocytes) and H3K27ac (n = 3 for female gametocytes) in female and male day 6 gametocytes for stage specifically expressed genes. Ring, female, and male specific genes represent clusters 1, 3, and 5, respectively, from Additional File 1: Figure S1. B Average log₂-transformed ChIP/Input coverage plots for H2A.Zac and H3K27ac in day 6 male and female gametocytes over genes that are upregulated after TSA treatment in early gametocytes (Ngwa et al. 2017, available as Supplementary Table 2), and all genes