Fig. 5
From: N-terminal region of Drosophila melanogaster Argonaute2 forms amyloid-like aggregates
Fractal-shaped Nter aggregates grew by docking between puncta. A–C Time-lapse images of the Nter aggregate formation. Ten-minute intervals are shown from left to right. Scale bars represent 5 μm (A, B) and 10 μm (C). D Model of the aggregate formation. Assuming both fibril- and fractal-shaped Nter aggregates grew from a single punctum, the polymerization of Nter monomers from the punctum results in fibril-shaped aggregates, while the fractal-shaped aggregates result from puncta binding to each other (i). The binding of several linear fractal-shaped aggregates produces branched fractal-shaped aggregates (ii). The branched fractal-shaped aggregate becomes bigger by docking with other fractal-shaped aggregates (iii)