Table 1 Top 50 brain regions specifically upregulated in the context of 5 μM AS1 and noxious heat (37.5 °C)

Telencephalon—Isl1 cluster 1

62,784.02

Telencephalon—Isl1 cluster 2

59,449.99

Telencephalon—Subpallial Otpb Cluster 2

57,862.31

Telencephalon—S1181t Cluster

55,333.89

Diencephalon—Eminentia Thalami

55,198.24

Telencephalon—Anterior Commisure

52,049.98

Telencephalon—Subpallial Gad1b cluster

51,995.37

Telencephalon—Olfactory bulb dopaminergic neuron areas

51,323.12

Telencephalon—Subpallium

50,437.3

Diencephalon—Otpb Cluster 2

48,466.37

Diencephalon—Retinal Arborization Field 4 (AF4)

47,600.85

Diencephalon—Oxtl Cluster 1 in Preoptic Area

47,413.8

Diencephalon—Retinal Arborization Field 2 (AF2- Approximate Location)

46,758.78

Diencephalon—Preoptic area Vglut2 cluster

46,521.07

Telencephalon—Vmat2 cluster

46,517.43

Telencephalon—Subpallial Otpb strip

45,224.41

Telencephalon—Subpallial dopaminergic cluster

44,557.21

Diencephalon—Retinal Arborization Field 3 (AF3)

43,716.94

Diencephalon—Dopaminergic Cluster 3—hypothalamus

40,019.12

Diencephalon—Isl1 cluster 1

39,266.09

Telencephalon -

38,670.72

Rhombencephalon—Glyt2 Cluster 8

38,553.58

Telencephalon—Subpallial Vglut2 Cluster

38,145.97

Diencephalon—Isl1 cluster 2

36,475.6

Telencephalon—Pallium

36,091.17

Diencephalon—Otpb Cluster 4

35,964.5

Diencephalon—Hypothalamus Qrfp neuron cluster

35,847.32

Rhombencephalon—Olig2 Cluster

35,771.76

Rhombencephalon—Gad1b Cluster 8

35,509.66

Diencephalon—Hypothalamus Hcrt Neurons

35,066.89

Telencephalon—Telencephalic Migrated Area 4 (M4)

35,038.42

Diencephalon—Oxtl Cluster 5

34,474.08

Diencephalon—Left Habenula Vglut2 Cluster

33,383.12

Rhombencephalon—Glyt2 Cluster 7

33,307.91

Diencephalon—Oxtl Cluster 2

32,549.34

Rhombencephalon—MiM1

32,356.03

Diencephalon—Dopaminergic Cluster 1—ventral thalamic and periventricular posterior tubercular DA neurons

31,653.23

Diencephalon—Hypothalamus s1181t Cluster

30,757.2

Telencephalon—Vglut2 rind

30,426.53

Mesencephalon—Vmat2 cluster2

28,483.57

Diencephalon—Olig2 Band 2

27,055.59

Rhombencephalon—Spiral Fiber Neuron Posterior cluster

26,252.82

Rhombencephalon—Mauthner

26,157.52

Diencephalon—Preoptic Area

26,037.78

Rhombencephalon—Gad1b Cluster 6

25,823.45

Telencephalon—Olig2 Cluster

25,415.34

Telencephalon—Olfactory Bulb

24,123.37

Diencephalon—Otpb Cluster 3

23,189.83

Rhombencephalon—Vglut2 cluster 1

23,112.53

Diencephalon—Ventral Thalamus

22,613.96