Fig. 3
From: Fear-of-intimacy-mediated zinc transport is required for Drosophila fat body endoreplication
Modulation of zinc transporters altered the developmental defects of foi RNAi. A The eclosion defect of Cg-Gal4 > foi RNAi larvae was partially rescued by dZip1 OE. n = 50–70 larvae per vial, n = 6 vials per experimental group. B The reduced fat body size of Cg-Gal4 > foi RNAi larvae was partially rescued by dZip1 OE and exacerbated by dZnT1 OE. n = 6 replicates per group. Genotypes used in (A-B) were Cg-Gal4 > w1118 (control), Cg-Gal4 > foi RNAi, Cg-Gal4 > foi RNAi; dZip1 OE, Cg-Gal4 > dZnT1 OE; foi RNAi, Cg-Gal4 > dZip1 OE, Cg-Gal4 > dZnT1 OE. C The reduced fat body cell size of Cg-Gal4 > foi RNAi larvae was significantly rescued by dZip1 OE. n = 6 replicates per group. Scale bar, 100 μm. D Quantitative measurement of the fat body cell sizes in (C). n = 6 replicates per group. Genotypes used in (C-D) were Cg-Gal4 > w1118 (control), Cg-Gal4 > foi RNAi, Cg-Gal4 > foi RNAi; dZip1 OE, Cg-Gal4 > dZip1 OE. n = 6 replicates per group. Data are presented as mean ± SEM of the biological replicates. ***p < 0.001; two-tailed Student’s t-test. OE, overexpression